Mathematics Stack Exchange is a question and answer site for people studying math at any level and professionals in related fields. What is the probability that exactly one unit is defective? My answer would be.Inhibition of cyclin-dependent kinase 1 (CDK1) by phosphorylation is a key regulatory mechanism for both the unperturbed cell cycle and the DNA damage The acceleration of checkpoint recovery in MYT1-depleted cells was due to a lowering of threshold for CDK1 activation. The kinase activity of...Add your answer and earn points. jamuuj jamuuj. If the kinase that adds the inhibitory phosphate to cdk were defective then the M phase would begin prematurely.Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II)...1.Walk me through the 3 financial statements. "The 3 major financial statements are the Income Statement, Balance Sheet and Cash Flow Statement. The Income Statement gives the company's revenue and expenses, and goes down to Net Income, the final line on the statement.
The CDK1 inhibitory kinase MYT1 in DNA damage checkpoint recovery
Cyclin dependent kinase 5 is a protein, and more specifically an enzyme, that is encoded by the Cdk5 gene. It was discovered 15 years ago and it is saliently expressed in post-mitotic central nervous system neurons (CNS). The molecule belongs to the cyclin-dependent kinase family.Cyclin bound to Cdk with this inhibitory phosphate indicated in yellow. And these are the sorts of systems for which dynamical mathematical models are really required to to get good understanding and to make quantitative predictions about what's going to happen if you were to say you know, change...To be very clear, there's no science to support what Dr. Wolfson is claiming. But what would happen if we all stopped vaccinating ourselves and our kids? What would you say are the key forces that are leading us down that road? Our misguided respect for individual choice. I mean, I just don't get it.A Abraham Lincoln is regarded as one of America's greatest heroes due to both his incredible impact on the nation and his unique appeal. His story is a remarkable rise from humble beginnings to achieve the highest office in the land; then, a sudden and tragic death at a time when his country needed him...
What would happen if the kinase that adds the inhibitory...
This flashcard is meant to be used for studying, quizzing and learning new information. Many scouting web questions are common questions that are typically seen in the classroom, for homework or on quizzes and tests. Flashcards vary depending on the topic, questions and age group....inhibitory phosphate to cdk were defective? see section 12.3 (page 264) . view available hint(s) what see section 12.3 (page 264) . the onset of m phase would be delayed. cdk concentrations would Cdks are kinases, enzymes that phosphorylate (attach phosphate groups to) specific target...b)If we add an inhibitor into the cell that inhibits CAK's function, what will happen to M-Cdk and cell cycle? inactive phosphatase Cdc25 POSITIVE FEEDBACK M-cyclin inhibitory phosphate Cdk-activating kinase CAK Cdc25 activating phosphate Wee1 Cdk1 inactive M-Cdk Cdk-inhibitory...Chapter 12 Reading Quiz Question 9 Part AWhat two types of defects does a cancerous cell possess?You did not open hints for this part. Chapter 12 Blue Thread Question 10Part AWhat would happen if the kinase that adds the inhibitory phosphate to Cdk were defective?You did not open...Cyclin-dependent kinases (CDKs) are protein kinases characterized by needing a separate subunit - a cyclin - that provides domains essential for enzymatic activity. CDKs play important roles in the control of cell division and modulate transcription in response to several extra- and intracellular cues.
1.
Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S: The protein kinase complement of the human genome. Science. 2002, 298: 1912-1934. 10.1126/science.1075762.
PubMed CAS Article Google Scholar
2.Malumbres M, Harlow E, Hunt T, Hunter T, Lahti JM, Manning G, Morgan DO, Tsai LH, Wolgemuth DJ: Cyclin-dependent kinases: a circle of relatives portrait. Nat Cell Biol. 2009, 11: 1275-1276. 10.1038/ncb1109-1275.
PubMed CAS PubMed Central Article Google Scholar
3.Malumbres M, Barbacid M: Mammalian cyclin-dependent kinases. Trends Biochem Sci. 2005, 30: 630-641. 10.1016/j.tibs.2005.09.005.
PubMed CAS Article Google Scholar
4.Morgan DO: Cyclin-dependent kinases: engines, clocks, and microprocessors. Annu Rev Cell Dev Biol. 1997, 13: 261-291. 10.1146/annurev.cellbio.13.1.261.
PubMed CAS Article Google Scholar
5.Lim S, Kaldis P: Cdks, cyclins and CKIs: roles past mobile cycle regulation. Development. 2013, 140: 3079-3093. 10.1242/dev.091744.
PubMed CAS Article Google Scholar
6.Malumbres M, Barbacid M: Cell cycle, CDKs and cancer: a changing paradigm. Nat Rev Cancer. 2009, 9: 153-166. 10.1038/nrc2602.
PubMed CAS Article Google Scholar
7.Cao L, Chen F, Yang X, Xu W, Xie J, Yu L: Phylogenetic analysis of CDK and cyclin proteins in premetazoan lineages. BMC Evol Biol. 2014, 14: 10-10.1186/1471-2148-14-10.
PubMed PubMed Central Article Google Scholar
8.Liu J, Kipreos ET: Evolution of cyclin-dependent kinases (CDKs) and CDK-activating kinases (CAKs): differential conservation of CAKs in yeast and metazoa. Mol Biol Evol. 2000, 17: 1061-1074. 10.1093/oxfordjournals.molbev.a026387.
PubMed CAS Article Google Scholar
9.Santamaria D, Barriere C, Cerqueira A, Hunt S, Tardy C, Newton K, Caceres JF, Dubus P, Malumbres M, Barbacid M: Cdk1 is enough to drive the mammalian mobile cycle. Nature. 2007, 448: 811-815. 10.1038/nature06046.
PubMed CAS Article Google Scholar
10.Ortega S, Prieto I, Odajima J, Martin A, Dubus P, Sotillo R, Barbero JL, Malumbres M, Barbacid M: Cyclin-dependent kinase 2 is essential for meiosis but no longer for mitotic cellular division in mice. Nat Genet. 2003, 35: 25-31. 10.1038/ng1232.
PubMed CAS Article Google Scholar
11.Huang D, Friesen H, Andrews B: Pho85, a multifunctional cyclin-dependent protein kinase in budding yeast. Mol Microbiol. 2007, 66: 303-314. 10.1111/j.1365-2958.2007.05914.x.
PubMed CAS Article Google Scholar
12.Davidson G, Shen J, Huang YL, Su Y, Karaulanov E, Bartscherer Ok, Hassler C, Stannek P, Boutros M, Niehrs C: Cell cycle keep watch over of wnt receptor activation. Dev Cell. 2009, 17: 788-799. 10.1016/j.devcel.2009.11.006.
PubMed CAS Article Google Scholar
13.Mikolcevic P, Rainer J, Geley S: Orphan kinases flip eccentric: a new class of cyclin Y-activated, membrane-targeted CDKs. Cell Cycle. 2012, 11: 3758-3768. 10.4161/cc.21592.
PubMed CAS PubMed Central Article Google Scholar
14.Harashima H, Dissmeyer N, Schnittger A: Cell cycle keep watch over across the eukaryotic kingdom. Trends Cell Biol. 2013, 23: 345-356. 10.1016/j.tcb.2013.03.002.
PubMed CAS Article Google Scholar
15.Carlsten JO, Zhu X, Gustafsson CM: The multitalented Mediator complex. Trends Biochem Sci. 2013, 38: 531-537. 10.1016/j.tibs.2013.08.007.
PubMed CAS Article Google Scholar
16.Kohoutek J, Blazek D: Cyclin Okay goes with Cdk12 and Cdk13. Cell Div. 2012, 7: 12-10.1186/1747-1028-7-12.
PubMed CAS PubMed Central Article Google Scholar
17.Guo Z, Stiller JW: Comparative genomics of cyclin-dependent kinases suggest co-evolution of the RNAP II C-terminal area and CTD-directed CDKs. BMC Genomics. 2004, 5: 69-10.1186/1471-2164-5-69.
PubMed PubMed Central Article Google Scholar
18.Echalier A, Endicott JA, Noble ME: Recent developments in cyclin-dependent kinase biochemical and structural research. Biochim Biophys Acta. 1804, 2010: 511-519.
Google Scholar
19.Pavletich NP: Mechanisms of cyclin-dependent kinase regulation: constructions of Cdks, their cyclin activators, and Cip and INK4 inhibitors. J Mol Biol. 1999, 287: 821-828. 10.1006/jmbi.1999.2640.
PubMed CAS Article Google Scholar
20.Day PJ, Cleasby A, Tickle IJ, O'Reilly M, Coyle JE, Holding FP, McMenamin RL, Yon J, Chopra R, Lengauer C, Jhoti H: Crystal structure of human CDK4 in advanced with a D-type cyclin. Proc Natl Acad Sci U S A. 2009, 106: 4166-4170. 10.1073/pnas.0809645106.
PubMed CAS PubMed Central Article Google Scholar
21.Takaki T, Echalier A, Brown NR, Hunt T, Endicott JA, Noble ME: The construction of CDK4/cyclin D3 has implications for fashions of CDK activation. Proc Natl Acad Sci U S A. 2009, 106: 4171-4176. 10.1073/pnas.0809674106.
PubMed CAS PubMed Central Article Google Scholar
22.Mikolcevic P, Sigl R, Rauch V, Hess MW, Pfaller Ok, Barisic M, Pelliniemi LJ, Boesl M, Geley S: Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis. Mol Cell Biol. 2012, 32: 868-879. 10.1128/MCB.06261-11.
PubMed CAS PubMed Central Article Google Scholar
23.Boutros R, Lobjois V, Ducommun B: CDC25 phosphatases in most cancers cells: key players? Good targets?. Nat Rev Cancer. 2007, 7: 495-507. 10.1038/nrc2169.
PubMed CAS Article Google Scholar
24.Jeffrey PD, Tong L, Pavletich NP: Structural foundation of inhibition of CDK-cyclin complexes through INK4 inhibitors. Genes Dev. 2000, 14: 3115-3125. 10.1101/gad.851100.
PubMed CAS PubMed Central Article Google Scholar
25.Malumbres M, Barbacid M: To cycle or now not to cycle: a essential resolution in most cancers. Nat Rev Cancer. 2001, 1: 222-231. 10.1038/35106065.
PubMed CAS Article Google Scholar
26.Rubin SM: Deciphering the retinoblastoma protein phosphorylation code. Trends Biochem Sci. 2013, 38: 12-19. 10.1016/j.tibs.2012.10.007.
PubMed CAS PubMed Central Article Google Scholar
27.Malumbres M, Sotillo R, Santamaria D, Galan J, Cerezo A, Ortega S, Dubus P, Barbacid M: Mammalian cells cycle with out the D-type cyclin-dependent kinases Cdk4 and Cdk6. Cell. 2004, 118: 493-504. 10.1016/j.mobile.2004.08.002.
PubMed CAS Article Google Scholar
28.Cheung ZH, Ip NY: Cdk5: a multifaceted kinase in neurodegenerative illnesses. Trends Cell Biol. 2012, 22: 169-175. 10.1016/j.tcb.2011.11.003.
PubMed CAS Article Google Scholar
29.Arif A: Extraneuronal activities and regulatory mechanisms of the peculiar cyclin-dependent kinase Cdk5. Biochem Pharmacol. 2012, 84: 985-993. 10.1016/j.bcp.2012.06.027.
PubMed CAS Article Google Scholar
30.Liu Y, Cheng Okay, Gong Ok, Fu AK, Ip NY: Pctaire1 phosphorylates N-ethylmaleimide-sensitive fusion protein: implications in the legislation of its hexamerization and exocytosis. J Biol Chem. 2006, 281: 9852-9858. 10.1074/jbc.M513496200.
PubMed CAS Article Google Scholar
31.Davidson G, Niehrs C: Emerging links between CDK cellular cycle regulators and Wnt signaling. Trends Cell Biol. 2010, 20: 453-460. 10.1016/j.tcb.2010.05.002.
PubMed CAS Article Google Scholar
32.Egloff S, Dienstbier M, Murphy S: Updating the RNA polymerase CTD code: adding gene-specific layers. Trends Genet. 2012, 28: 333-341. 10.1016/j.tig.2012.03.007.
PubMed CAS Article Google Scholar
33.Egly JM, Coin F: A history of TFIIH: 20 years of molecular biology on a pivotal transcription/repair component. DNA Repair (Amst). 2011, 10: 714-721. 10.1016/j.dnarep.2011.04.021.
CAS Article Google Scholar
34.Larochelle S, Amat R, Glover-Cutter Ok, Sanso M, Zhang C, Allen JJ, Shokat KM, Bentley DL, Fisher RP: Cyclin-dependent kinase regulate of the initiation-to-elongation transfer of RNA polymerase II. Nat Struct Mol Biol. 2012, 19: 1108-1115. 10.1038/nsmb.2399.
PubMed CAS PubMed Central Article Google Scholar
35.Bres V, Yoh SM, Jones KA: The multi-tasking P-TEFb complex. Curr Opin Cell Biol. 2008, 20: 334-340. 10.1016/j.ceb.2008.04.008.
PubMed CAS PubMed Central Article Google Scholar
36.Bartkowiak B, Liu P, Phatnani HP, Fuda NJ, Cooper JJ, Price DH, Adelman K, Lis JT, Greenleaf AL: CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1. Genes Dev. 2010, 24: 2303-2316. 10.1101/gad.1968210.
PubMed CAS PubMed Central Article Google Scholar
37.Blazek D, Kohoutek J, Bartholomeeusen K, Johansen E, Hulinkova P, Luo Z, Cimermancic P, Ule J, Peterlin BM: The Cyclin Ok/Cdk12 complex maintains genomic balance by way of regulation of expression of DNA injury reaction genes. Genes Dev. 2011, 25: 2158-2172. 10.1101/gad.16962311.
PubMed CAS PubMed Central Article Google Scholar
38.Clemente-Blanco A, Sen N, Mayan-Santos M, Sacristan MP, Graham B, Jarmuz A, Giess A, Webb E, Game L, Eick D, Bueno A, Merkenschlager M, Aragon L: Cdc14 phosphatase promotes segregation of telomeres thru repression of RNA polymerase II transcription. Nat Cell Biol. 2011, 13: 1450-1456. 10.1038/ncb2365.
PubMed CAS PubMed Central Article Google Scholar
39.Guillamot M, Manchado E, Chiesa M, Gomez-Lopez G, Pisano DG, Sacristan MP, Malumbres M: Cdc14b regulates mammalian RNA polymerase II and represses mobile cycle transcription. Sci Rep. 2011, 1: 189-
PubMed PubMed Central Article Google Scholar
40.Galbraith MD, Donner AJ, Espinosa JM: CDK8: a positive regulator of transcription. Transcription. 2010, 1: 4-12. 10.4161/trns.1.1.12373.
PubMed CAS PubMed Central Article Google Scholar
41.Sato S, Tomomori-Sato C, Parmely TJ, Florens L, Zybailov B, Swanson SK, Banks CA, Jin J, Cai Y, Washburn MP, Conaway JW, Conaway RC: A collection of consensus mammalian mediator subunits identified by multidimensional protein identity generation. Mol Cell. 2004, 14: 685-691. 10.1016/j.molcel.2004.05.006.
PubMed CAS Article Google Scholar
42.Hu D, Mayeda A, Trembley JH, Lahti JM, Kidd VJ: CDK11 complexes advertise pre-mRNA splicing. J Biol Chem. 2003, 278: 8623-8629. 10.1074/jbc.M210057200.
PubMed CAS Article Google Scholar
43.Drogat J, Migeot V, Mommaerts E, Mullier C, Dieu M, van Bakel H, Hermand D: Cdk11-cyclinL controls the assembly of the RNA polymerase II mediator complicated. Cell Rep. 2012, 2: 1068-1076. 10.1016/j.celrep.2012.09.027.
PubMed CAS Article Google Scholar
44.Wilkinson S, Croft DR, O'Prey J, Meedendorp A, O'Prey M, Dufes C, Ryan KM: The cyclin-dependent kinase PITSLRE/CDK11 is needed for successful autophagy. Autophagy. 2011, 7: 1295-1301. 10.4161/auto.7.11.16646.
PubMed CAS PubMed Central Article Google Scholar
45.Wang Y, Zong H, Chi Y, Hong Y, Yang Y, Zou W, Yun X, Gu J: Repression of estrogen receptor alpha by CDK11p58 through selling its ubiquitin-proteasome degradation. J Biochem. 2009, 145: 331-343. 10.1093/jb/mvn177.
PubMed CAS Article Google Scholar
46.Chi Y, Hong Y, Zong H, Wang Y, Zou W, Yang J, Kong X, Yun X, Gu J: CDK11p58 represses diet D receptor-mediated transcriptional activation thru selling its ubiquitin-proteasome degradation. Biochem Biophys Res Commun. 2009, 386: 493-498. 10.1016/j.bbrc.2009.06.061.
PubMed CAS Article Google Scholar
47.Petretti C, Savoian M, Montembault E, Glover DM, Prigent C, Giet R: The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation. EMBO Rep. 2006, 7: 418-424.
PubMed CAS PubMed Central Google Scholar
48.Hu D, Valentine M, Kidd VJ, Lahti JM: CDK11(p58) is required for the maintenance of sister chromatid cohesion. J Cell Sci. 2007, 120: 2424-2434. 10.1242/jcs.007963.
PubMed CAS Article Google Scholar
49.Yokoyama H, Gruss OJ, Rybina S, Caudron M, Schelder M, Wilm M, Mattaj IW, Karsenti E: Cdk11 is a RanGTP-dependent microtubule stabilization element that regulates spindle meeting fee. J Cell Biol. 2008, 180: 867-875. 10.1083/jcb.200706189.
PubMed CAS PubMed Central Article Google Scholar
50.Guen VJ, Gamble C, Flajolet M, Unger S, Thollet A, Ferandin Y, Superti-Furga A, Cohen PA, Meijer L, Colas P: CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is poor in STAR syndrome. Proc Natl Acad Sci U S A. 2013, 110: 19525-19530. 10.1073/pnas.1306814110.
PubMed CAS PubMed Central Article Google Scholar
51.Liu W, Cai MJ, Wang JX, Zhao XF: In a non-genomic action, steroid hormone 20-hydroxyecdysone induces phosphorylation of cyclin-dependent kinase 10 to advertise gene transcription. Endocrinology. 2014, 155: 1738-1750. 10.1210/en.2013-2020.
PubMed Article Google Scholar
52.Wohlbold L, Larochelle S, Liao JC, Livshits G, Singer J, Shokat KM, Fisher RP: The cyclin-dependent kinase (CDK) family member PNQALRE/CCRK helps cellular proliferation however has no intrinsic CDK-activating kinase (CAK) job. Cell Cycle. 2006, 5: 546-554. 10.4161/cc.5.5.2541.
PubMed CAS Article Google Scholar
53.Fu Z, Larson KA, Chitta RK, Parker SA, Turk BE, Lawrence MW, Kaldis P, Galaktionov K, Cohn SM, Shabanowitz J, Hunt DF, Sturgill TW: Identification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase. Mol Cell Biol. 2006, 26: 8639-8654. 10.1128/MCB.00816-06.
PubMed CAS PubMed Central Article Google Scholar
54.Feng H, Cheng AS, Tsang DP, Li MS, Go MY, Cheung YS, Zhao GJ, Ng SS, Lin MC, Yu J, Lai PB, To KF, Sung JJ: Cell cycle-related kinase is a direct androgen receptor-regulated gene that drives beta-catenin/T cellular factor-dependent hepatocarcinogenesis. J Clin Invest. 2011, 121: 3159-3175. 10.1172/JCI45967.
PubMed CAS PubMed Central Article Google Scholar
55.Yang Y, Roine N, Makela TP: CCRK depletion inhibits glioblastoma cell proliferation in a cilium-dependent approach. EMBO Rep. 2013, 14: 741-747. 10.1038/embor.2013.80.
PubMed CAS PubMed Central Article Google Scholar
56.Aleem E, Kiyokawa H, Kaldis P: Cdc2-cyclin E complexes keep an eye on the G1/S segment transition. Nat Cell Biol. 2005, 7: 831-836. 10.1038/ncb1284.
PubMed CAS Article Google Scholar
57.Kollmann Okay, Heller G, Schneckenleithner C, Warsch W, Scheicher R, Ott RG, Schafer M, Fajmann S, Schlederer M, Schiefer AI, Reichart U, Mayerhofer M, Hoeller C, Zochbauer-Muller S, Kerjaschki D, Bock C, Kenner L, Hoefler G, Freissmuth M, Green AR, Moriggl R, Busslinger M, Malumbres M, Sexl V: A kinase-independent serve as of CDK6 links the cellular cycle to tumor angiogenesis. Cancer Cell. 2013, 24: 167-181. 10.1016/j.ccr.2013.07.012.
PubMed CAS PubMed Central Article Google Scholar
58.Handschick Ok, Beuerlein Okay, Jurida L, Bartkuhn M, Muller H, Soelch J, Weber A, Dittrich-Breiholz O, Schneider H, Scharfe M, Jarek M, Stellzig J, Schmitz ML, Kracht M: Cyclin-dependent kinase 6 is a chromatin-bound cofactor for NF-kappaB-dependent gene expression. Mol Cell. 2014, 53: 193-208. 10.1016/j.molcel.2013.12.002.
PubMed CAS Article Google Scholar
59.Breakthrough treatments. http://www.focr.org/breakthrough-therapies,
60.Firestein R, Bass AJ, Kim SY, Dunn IF, Silver SJ, Guney I, Freed E, Ligon AH, Vena N, Ogino S, Chheda MG, Tamayo P, Finn S, Shrestha Y, Boehm JS, Jain S, Bojarski E, Mermel C, Barretina J, Chan JA, Baselga J, Tabernero J, Root DE, Fuchs CS, Loda M, Shivdasani RA, Meyerson M, Hahn WC: CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity. Nature. 2008, 455: 547-551. 10.1038/nature07179.
PubMed CAS PubMed Central Article Google Scholar
61.Morris EJ, Ji JY, Yang F, Di Stefano L, Herr A, Moon NS, Kwon EJ, Haigis KM, Naar AM, Dyson NJ: E2F1 represses beta-catenin transcription and is antagonized via both pRB and CDK8. Nature. 2008, 455: 552-556. 10.1038/nature07310.
PubMed CAS PubMed Central Article Google Scholar
62.Iorns E, Turner NC, Elliott R, Syed N, Garrone O, Gasco M, Tutt AN, Crook T, Lord CJ, Ashworth A: Identification of CDK10 as the most important determinant of resistance to endocrine therapy for breast most cancers. Cancer Cell. 2008, 13: 91-104. 10.1016/j.ccr.2008.01.001.
PubMed CAS Article Google Scholar
63.Bajrami I, Frankum JR, Konde A, Miller RE, Rehman FL, Brough R, Campbell J, Sims D, Rafiq R, Hooper S, Chen L, Kozarewa I, Assiotis I, Fenwick Okay, Natrajan R, Lord CJ, Ashworth A: Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity. Cancer Res. 2014, 74: 287-297. 10.1158/0008-5472.CAN-13-2541.
PubMed CAS Article Google Scholar
64.Leung WK, Ching AK, Chan AW, Poon TC, Mian H, Wong AS, To KF, Wong N: A singular interplay between oncogenic PFTK1 protein kinase and tumor suppressor TAGLN2 in the keep watch over of liver cancer mobile motility. Oncogene. 2011, 30: 4464-4475. 10.1038/onc.2011.161.
PubMed CAS Article Google Scholar
65.Huang J, Deng Q, Wang Q, Li KY, Dai JH, Li N, Zhu ZD, Zhou B, Liu XY, Liu RF, Fei QL, Chen H, Cai B, Xiao HS, Qin LX, Han ZG: Exome sequencing of hepatitis B virus-associated hepatocellular carcinoma. Nat Genet. 2012, 44: 1117-1121. 10.1038/ng.2391.
PubMed CAS Article Google Scholar
66.Ma Z, Wu Y, Jin J, Yan J, Kuang S, Zhou M, Zhang Y, Guo AY: Phylogenetic research finds the evolution and diversification of cyclins in eukaryotes. Mol Phylogenet Evol. 2013, 66: 1002-1010. 10.1016/j.ympev.2012.12.007.
PubMed CAS Article Google Scholar
67.Chen J, Larochelle S, Li X, Suter B: Xpd/Ercc2 regulates CAK activity and mitotic progression. Nature. 2003, 424: 228-232. 10.1038/nature01746.
PubMed CAS Article Google Scholar
Proteins that degrade cyclin are activated by events that ...
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